Regulated information & Press releases
- Cabozantinib is the first and only monotherapy to demonstrate superior clinical efficacy over sunitinib in treatment-naïve patients with intermediate- or poor-risk aRCC
- For patients living with neuroendocrine tumors, insufficiently controlled carcinoid syndrome can be a major burden that severely impacts quality of life[1]
- Xermelo® (telotristat ethyl) 250mg demonstrates sustained improvement of carcinoid syndrome diarrhea when associated with somatostatin analogues (SSA)
- Xermelo® is a first-in-class tryptophan hydroxylase inhibitor in convenient oral form with a favorable safety profile
- Independent Radiology Review Committee confirms primary endpoint analysis per investigator: cabozantinib provided statistically significant improvement of progression-free survival, with a 52 percent reduction in the rate of progression or death compared to sunitinib
- Ipsen and Exelixis will host an investor and media webcast from Madrid to discuss the data on Sunday, September 10 starting at 18h45 CEST
- Cabometyx® is an innovative molecule already approved by EMA for the treatment of advanced renal cell carcinoma (aRCC) in adults following prior VEGF-targeted therapy.
- The filing in first line aRCC is based on the CABOSUN results, a phase II trial demonstrating that Cabometyx® prolongs progression-free survival (PFS) in treatment-naive patients with intermediate- or poor-risk advanced RCC compared to sunitinib.[i]
- Positive opinion based on the results of two randomized Phase 3 trials, TELESTAR and TELECAST
Half-year IPSEN liquidity contract statement entered into with NATIXIS
Download ( pdf - 141 kB)
– First phase 3 trial in a global clinical development program to explore the combination of these agents –
– Exelixis, Bristol-Myers Squibb and Ipsen to co-fund this trial –
Download ( pdf - 188 kB)
IRC confirms cabozantinib significantly improved progression-free survival compared to sunitinib
E.U. regulatory submission remains on track for Q3 2017
Download ( pdf - 338 kB)- Significantly expands Ipsen’s growing oncology portfolio
- Immediate U.S. commercialization rights for ONIVYDE® for metastatic pancreatic cancer in adult patients[1]
Strong operating performance exceeds guidance with Group sales up 11.8% driven by Specialty Care and Core Operating Margin improvement despite Cabometyx launch investments
Acquisition of Onivyde and new Primary Care products expected to close during the first half of 2017
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Download transcript ( pdf - 205 kB)
Ipsen today announced the appointment of Harout Semerjian as President, Head of Specialty Care International Region & Global Franchises, effective February 2, 2017. He will report to David Meek, CEO of Ipsen, and will be a member of the Executive Leadership Team.
Download ( pdf - 219 kB)Half-year IPSEN liquidity contract statement entered into with NATIXIS
Download ( pdf - 136 kB)Under the terms of the agreement, Ipsen will gain exclusive commercialization rights for the current and potential future ONIVYDE indications in the U.S., as well as the current licensing agreements with Shire for commercialization rights ex-U.S. and PharmaEngine for Taiwan. The transaction also includes Merrimack’s commercial and manufacturing infrastructure, and generic doxorubicin HCl liposome injection.
Download the press release ( pdf - 82 kB)Download the presentation ( pdf - 897 kB)
- Amendment enhances productive year with CABOMETYXTM regulatory approvals and commercial launches in the United States and European Union
- Exelixis to receive $10 million upfront payment, with subsequent regulatory and commercial milestones
- Acceleration of Group sales growth at 12.2%1 in the third quarter resulting in 10.5%1 sales growth for the first 9 months driven by Specialty Care
- Guidance 2016 raised